Vibrio is a genus of Gram-negative bacteria characterized by their distinctive curved, comma-shaped rods and flagellar motility, enabling them to move efficiently in aquatic environments. Commonly found in marine and estuarine waters, these microorganisms thrive in warm, brackish conditions and can form biofilms on surfaces like shellfish. Several species are pathogenic to humans, most notably Vibrio cholerae, which causes cholera through toxin production leading to severe diarrhea and dehydration. Other species, such as Vibrio vulnificus and Vibrio parahaemolyticus, are associated with wound infections and gastroenteritis from consuming contaminated seafood. Vibrios play ecological roles in nutrient cycling but pose public health risks, often mitigated by proper food handling and water sanitation practices. Research continues on their antibiotic resistance and climate change impacts.